Some villains are addicted to drugs, alcohol, or any other substance, or even a certain activity and also their behavior. Thus, these Addicts can be considered a variation of a Tragic villain due to the fact that their addiction may fuel their crimes and many can sympathize with them.

Many mental illness are worsened by drug and alcohol abuse, which is often one of the main reasons for violent psychosis - especially if coupled with Dissociation or Schizophrenic disorders : likewise prolonged use of drugs and alcohol can cause mental illness to manifest, as well as the more obvious dangers of chemical addiction (which in the case of alcohol is known as alcoholism).

Despite addiction being classed as an illness it is often stigmatized in society, especially in the case of alcoholism - with people seeing addicts as "drunkards" or "low-lives" who have brought misery upon themselves, some even use this as justification to abuse or kill such individuals as part of a twisted Social Darwinist ideal, some serial-killers also specifically target such individuals in order to "purify" society : this makes addicts a complicated matter for heroes and society as a whole, with varying degrees of sympathy being put forth depending on many factors.

However, some addicted characters otherwise go so far that they can lose their redeeming features and in the worst-case scenario become an Outright Villain or a Purely Evil villain.

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