Reality-Warpers are characters depicted with the power to alter reality itself, often on a large scale. These are characters that automatically have (at minimum) a planet-wide radius of influence; this means that many "cosmic" beings and higher-level super-beings count but lower-tiered beings (such as those who merely alter probability) are better suited to Elementals, Magic, or Paranormal.

By its very nature the "gift" of Reality-Warping (also known as Essokinesis, Ontokinesis and Realitokinesis), makes these characters have among the most powerful skills of all adversaries. These villains are such a force of nature, they range from planet-wide menaces, to becoming universal (and sometimes omniversal) threats on a godlike scale.

Some of these villains may even be nigh-omnipotent in a certain reality, all realities or villainous adaptations of God. Despite being super-powerful, they can still be conflicted and challenged by their heroic counterparts with similar power.